Detecting unsuspected HIV infection with a rapid whole-blood HIV test in an urban Emergency Department

Study evaluates and compares HIV screening and provider referred diagnostic testing as strategies for detecting undiagnosed HIV infection in an urban emergency department (ED). Concludes that ED screening detects HIV infection and links to care patients who may not be tested through risk- or symptom-based strategies. The diagnostic yield was higher among provider-referred patients, but screening detected patients earlier in the course of disease.

Detection of Acute HIV Infection: We Can’t Close the Window

Detection of acute HIV Infection: We can’t close the window. Journal of Infectious Diseases 2012;205:521–4. The authors discuss issues around testing for HIV in acute infection. They note reduction in the window period since the early days of HIV testing but state that it has not disappeared. Access to the whole editorial from this website is currently not available.

Evaluation of the Performance Characteristics of 6 Rapid HIV Antibody Tests

Evaluation of the performance characteristics of 6 rapid HIV antibody tests. Clinical Infectious Diseases 2011;52(2):257–263. Delaney and colleagues compare performance characteristics of the Clearview Complete, Clearview STAT-PAK,OraQuick Advance and Multispot HIV-1/2 tests plus the Reveal G3 and Uni-Gold Recombigen HIV-1 tests.

HIV on the Frontlines of Communities in the U.S. (HIV FOCUS) The Bridge Project Logic Model

This logic model describes a project from the AIDS Foundation of Chicago (AFC) and their key partner agencies - Brothers Health Collaborative (BHC), Beyond Care, MADE and the Chicago Department of Public Health. The project aims to: improve community health planning and population health status, decrease the number of undiagnosed Individuals and the number of late diagnosis of HIV and to ensure more HIV clients are linked to services.

HIV treatment can be HIV prevention

The U.S. AIDS epidemic is at a turning point. It’s been there before, first during the Reagan administration, which hoped to ignore AIDS but was shaken up by celebrity deaths and such courageous public servants as Dr. C. Everett Koop. Then, in the mid-’90s, drugs were developed that made HIV a manageable disease, but Food and Drug Administration approval lagged science until patients took to the streets.

Medscape - A Review of Medical Errors in Laboratory Diagnostics

A Review of Medical Errors in Laboratory Diagnostics and Where We Are Today 2012;43(2):41-44. © 2012 American Society for Clinical Pathology Sections: Abstract and Introduction; Quality Standards; Sources of Laboratory Error; Analytical Error; Pre-analytical Error ; Post-analytical Error; Monitoring Errors; Incident Reporting in Laboratory; Diagnostics &Conclusion

Medscape - Advances in HIV Testing: What Clinicians Need to Know

CDC Expert Commentary Advances in HIV Testing: What Clinicians Need to Know. Video and written commentary

Medscape - Parsing the Value of HIV At-Home Testing

Dr Paul Sax from Brigham and Women's Hospital and Harvard Medical School, on 13 July 2012, talks about the use of rapid HIV testing on oral fluid at home. At-home testing was approved in the United States in July 2012, by the Food and Drug Administration.

Medscape - Rapid Oral HIV Test Has Disadvantages

Medscape Medical News Rapid Oral HIV Test Has Disadvantages. Commentary on finding by two authors on PPV of rapid oral fluid test for HIV.

Medscape - Willingness to Take a Free Home HIV Test

Willingness to Take a Free Home HIV Test and Associated Factors Among Internet-Using Men Who Have Sex With Men. J Int Assoc Physicians AIDS Care. 2011;10(6):357-364. © 2011 Sage Publications, Inc.

Medscape -Factors Associated With Refusal of Rapid HIV Testing in an Emergency Department

Factors Associated With Refusal of Rapid HIV Testing in an Emergency Department. AIDS and Behavior. 2011;15(4):734-742. © 2011 Springer

Rapid HIV tests: guidelines for use in HIV testing and counselling services in resource- constrained settings

This document reviews the characteristics of rapid HIV tests which make them suitable for HIV testing and counselling services and discusses practical aspects of their use. Consideration is given to counselling issues, the advantages of rapid tests and the precautions necessary in using them. Testing algorithms for the use of rapid tests and current WHO recommendations are presented. Although rapid HIV tests have been developed which use saliva and urine, this document concentrates on tests involving the use of whole blood, serum or plasma.

Screening for Acute HIV Infection: Lessons Learned

Screening for Acute HIV Infection: Lessons Learned. Clinical Infectious Diseases 2007; 44:459–61. Stekler and colleagues report cases involving 3 individuals tested for acute HIV infection to describe unusual situations in acute HIV testing and to illustrate the importance of risk assessment in the interpretation of HIV test results.

Targeted HIV testing program finds thousands of new patients

27 June 2011 A three-year effort to test for HIV in hospital emergency rooms, drug treatment centers, venereal disease clinics and other places with high-risk populations identified about 18,000 new infected people and enrolled three-quarters of them in treatment, federal officials said Thursday.

The Lancet Infectious Diseases - Head-to-head comparison of accuracy of a rapid point-of-care HIV test with oral versus whole-blood specimens: a systematic review and meta-analysis

The Lancet Infectious Diseases, Volume 12, Issue 5, Pages 373 - 380, May 2012 See commentary on Medscape - Rapid Oral HIV Test Has Disadvantages

UK National Guidelines for HIV Testing 2008

These guidelines provide the information needed to enable any clinician to perform an HIV test within good clinical practice and encourage ’normalisation‘ of HIV testing. This guidance refers to both diagnostic testing of individuals presenting with ‘clinical indicator diseases’ (i.e. where HIV infection enters the differential diagnosis) and opportunistic screening of populations where this is indicated on the basis of prevalence data. We also include an appendix on the provision of community-based HIV testing (Appendix 3).

Undetectable Viral Load and Risk of HIV Transmission: ‘The Swiss Statement’

Date: December 2009; This factsheet addresses the relationship between HIV treatments, viral load levels, and the risk of sexual transmission of HIV. These issues have recently received a lot of attention in the HIV and community media and among people living with HIV (PLHIV) due to the publication of a statement from the Swiss Federal Commission for HIV/AIDS, which has subsequently become known as ‘the Swiss Statement’.

United States: opt-out HIV testing in clinical settings boosts HIV diagnoses among hard to reach groups

27 June 2011 Expanded HIV testing in the United States in clinical settings identified over 18,000 new HIV infections between October 2007 and September 2010, the US Centers for Disease Control and Prevention has reported. The new diagnoses were the result of targeting health care settings in areas with a large number of AIDS diagnoses in African-Americans.



Development of this site and the 2014 and 2017 revisions of the testing policies was supported by: Australian Government Department of Health and Ageing